“They rigorously proved over the course of three or four years that the single cell that gave rise to the spleen colony bumps could self renew and could give rise to all the different types of mature blood cells,” (source: The healthzone.ca) ... "Their work in the 1960s also paved the way for bone marrow transplantation for cancer patients."
McCulloch wanted to cure leukemia, and his discovery has indeed led to many being cured from it, including this blogger. However, there is much more work to be done to improve survival rates, and reduction in graft versus host disease (gvhd), i.e., the acute and chronic side effect problems, that can be harsh. Stem cell or bone marrow transplants can save lives, allow some to lead normal lives, and cure cancer. However, transplants do not always work, because for one thing, the donor/patient match may not be compatible enough. At other times, they do work but do cause gvhd, which can be life changing.
My gratitude was given to my amazing donor, but now posthumously to Dr. McCulloch who passed away last week at the age of 85. McCulloch and Till's award winning and diligent research has given hope to many who face blood cancers.
You too can give hope and save a life, not just through being a blood donor, but being a stem cell donor. A blood test is taken and the specific (HLA) characteristics and matching criteria are recorded in a registry bank. There could well be a person who needs your exact blood match.
If interested please see the contact information below. You can find out more at the OneMatch Stem Cell and Marrow Network, Canada
Canadian Blood Services
1800 Alta Vista Drive
K1G 4J5 Ottawa, Ontario
Canada TEL: +1-613-739-2435